Treatment of primary myelofibrosis in patients with symptoms may include the following:
- Transfusion of red blood cells to relieve symptoms and improve quality of life
- Biologic therapy using interferon alfa or erythropoietic growth factors
- Radiation therapy to the spleen
- Donor stem cell transplant
- Thalidomide or lenalidomide
- A clinical trial of a new treatment
Treatment of primary myelofibrosis in patients without symptoms is usually watchful waiting.