Treatment

Treatment of primary myelofibrosis in patients without symptoms is usually watchful waiting. Treatment of primary myelofibrosis in patients with symptoms may include the following:

  • Transfusion of red blood cells to relieve symptoms and improve quality of life
  • Biologic therapy using interferon alfa or erythropoietic growth factors
  • Splenectomy
  • Radiation therapy to the spleen
  • Chemotherapy
  • Donor stem cell transplant
  • Thalidomide or lenalidomide
  • A clinical trial of a new treatment